Products

Sanaria's mission is to develop and commercialize whole-parasite malaria vaccines that confer high-level, long-lasting protection against malaria caused by Plasmodium falciparum and P. vivax. In the process of developing these vaccines, Sanaria has developed the capacity to manufacture and assay malaria parasites and mosquitoes in a highly regulated, cGMP compliant, industrial setting. These parasites, mosquitoes, and assay services are now available to the general research community as Sanaria announces the launch of its Sanaria ^® Family of Products and Services intended to advance and promote high quality research towards new malaria vaccines and drugs, diagnostics, and enhanced understanding of malaria pathology and immunobiology.

Products Available for Purchase

Sanaria^® Plasmodium falciparum Sporozoite Reagents

Aseptic, purified, vialed, cryopreserved, attenuated and non-attenuated Plasmodium falciparum (Pf) sporozoites.

Sanaria^® PfSPZ Challenge Mosquitoes

Live, aseptic and non-aseptic P. falciparum infected mosquitoes. These well-characterized mosquitoes are for experimentally challenging volunteers in studies assessing malaria vaccines and drugs and for laboratory-based research.

Sanaria^® Plasmodium Reagents

Purified, vialed, cryopreserved, attenuated and non-attenuated Plasmodium species sporozoites, as well as other life cycle stages for laboratory-based research studies.

Sanaria^® Plasmodium Reagent Slides

Slides for immunofluorescence assays to detect antibodies against purified sporozoite, and asexual erythrocytic, sexual erythrocytic and/or mosquito stages of Plasmodium species.

Sanaria^® Anopheles Reagents

Aseptic and non-aseptic Anopheles stephensi mosquitoes and derived material for laboratory-based research studies.

Sanaria^® Plasmodium Assay Services

Assessment of the effects of antibodies and drugs on the capacity of P. falciparum and P. vivax sporozoites to invade and develop in hepatocytes (inhibition of liver stage development assay), and of P. falciparum gametocytes to develop to oocysts and sporozoites in mosquitoes (transmission blocking assay). Assessment of antibodies to all life cycle stages of Plasmodium species by immunofluoresence assays and to selected antigens by ELISA.

Sanaria^® Recombinant Proteins and Antibodies

The following purified recombinant proteins are available: PfCSP, PvCSP, PfCelTOS, PvCelTOS, PyCelTOS, PfSSP2/TRAP, PfLSA-1, PfEXP-1, PfEBA-175, PyCSP. Monoclonal and/or polyclonal antibodies are available against PfCelTOS, PfEXP-1, PfCSP, PvCSP, and Pf sporozoites.

Sanaria^® Custom Services

Sanaria will manufacture Plasmodium species reagents to meet your specifications.

For pricing and other information please e-mail sales@sanaria.com.