Sanaria
Sanaria

Employment

Sanaria is currently expanding its activities and is accepting inquiries and resumes for the positions listed below. If you are interested in furthering your career with us please send the following information to careers@sanaria.com:

  • Cover letter
  • Resume or CV
  • Salary requirements

Sanaria is an equal opportunity employer.


AVAILABLE POSITIONS:

Molecular Biologist
Physician Investigator, Malabo, Equatorial Guinea
Manufacturing Manager
Research Associate Gametocyte Production
Calibration/Metrology Technician - Summer Intern/Employment

Molecular Biologist, Genome Editing in Mosquitoes and Malaria Parasites

Sanaria offers a unique and challenging opportunity for a molecular biologist to join a world-class team to work on the development and commercialization of our live sporozoite-based malaria vaccines. We are seeking a highly motivated, creative, hard-working, and enthusiastic individual with hands-on experience in CRISPR/Cas9 technology and molecular genetics. An initial responsibility will be the design and selection of guide RNAs, construction of donor DNA plasmids, and molecular characterization of mutant mosquito lines. Experience in molecular and cellular techniques essential for gene expression studies of constructed mosquito and parasite lines is required. The candidate will be an integral part of an in-house team of accomplished molecular biologists, parasitologists and entomologists and an expanding collaborative team that currently involves the Insect Transformation Facility at the University of Maryland Institute for Bioscience and Biotechnology Research and the University of Leiden (the Netherlands), and external consultants. The candidate will participate in GMP manufacturing of Sanaria's malaria vaccines.

Qualified candidates are expected to have Ph. D with a minimum of 3 years postgraduate experience in molecular biology and genome editing. Experience in mosquito or parasite biology and insect or parasite genetic transformation would be optimal. Excellent communication, writing, teamwork and organization skills and the willingness to learn new experimental and operational techniques are essential. Authorization to work in the US without sponsorship is required.


Physician Investigator, Malabo, Equatorial Guinea

The Physician Investigator will support Equatorial Guinea Malaria Vaccine Initiative (EGMVI) Stage 3 activities on site in Malabo, Equatorial Guinea for the duration of the project, approximately 2-3 years. The physician must be fully bilingual (written and spoken Spanish and English) and experienced in clinical research / field epidemiology. This position will be the local Sanaria project director, interact closely with onsite collaborators, partners and contractors, and assure that Sanaria's project objectives are met. Periodic visits to other sites in Africa, especially Tanzania, where Sanaria is sponsoring research trials, to represent Sanaria's interests in similar fashion, will be an important responsibility. The physician investigator will maintain frequent and comprehensive communication links with Sanaria Clinical personnel and report to the Chief Medical Officer.

Responsibilities

  • Liaise with EGMVI collaborators including other Sanaria staff on site to accomplish Sanaria's research objectives.
  • Assure adherence to Good Clinical Practices by all clinical research activities and personnel, with an emphasis on research volunteer safety.
  • Assure the integrity of all clinical data.
  • Carry out work plans / project activities, and maintain project timelines.
  • Support local protocol development, protocol approvals and clinical trial execution, including on-site monitoring and quality control.
  • Communicate regularly and frequently with Sanaria clinical staff.
  • Author written project reports and other documents.
  • Serve an ambassadorial function, promoting excellent collaborative relationships with partners and host nationals.
  • Attend meetings of the International PfSPZ Consortium and other meetings, as tasked.
  • Conduct at least yearly visits to Sanaria's contracted Occupational Health physician.

Qualifications

  • Doctor of Medicine degree and post-graduate medical training.
  • Licensure to practice medicine in home country.
  • 5+ years of clinical research / field epidemiology experience, ideally in the setting of international partnerships.
  • Good clinical practices certification.
  • Basic and advanced cardiac life support certification.
  • English and Spanish language fluency.
  • Preferred:
  • Ability to speak French.
  • Board certification in a primary care specialty (e.g. internal medicine, pediatrics, family medicine).
  • Infectious diseases fellowship training.

Work Environment

The incumbent will be housed in Equatorial Guinea and provided transportation and security according to the standards of our administrative partner Medical Care Development International (MCDI). MCDI maintains American and other foreign national staff full time in Malabo with security and health established as high priorities. Quality office space will be provided that is co-located with colleagues and collaborators to assure a congenial professional environment. Environmental hazards include potential exposure to human blood and to local disease hazards including identified and unidentified transmissible agents. Living in Equatorial Guinea may involve capricious events including police stops, local disturbances, inclement weather and travel hazards.

Manufacturing Manager

Sanaria's vaccine production is based on the life cycle of the parasite. Sanaria is producing material intended for Phase 3 trials and launch. Sanaria's manufacturing is a team-based environment.

The Manufacturing Manager will be working closely with individual manufacturing teams along with Quality and Operations to achieve Sanaria's manufacturing goals. The Manufacturing Manager will be responsible for the daily operations of Sanaria vaccine production reporting to the Executive Vice President of Process Development and Manufacturing.

Knowledge of aseptic operations and support systems is essential. A strong working knowledge of the regulatory compliance requirements for the production of biologics used in clinical studies and commercial manufacturing are essential. Demonstrated managerial skills, written and communication capabilities, and inter personal skills is necessary. The Manufacturing Manager must remain current regarding technical manufacturing requirements and must be able to develop/modifies production methods to fully address such issues. The Manufacturing Manager prepares validation protocols, SOPs, and master batch records. The Manufacturing Manager manages manufacturing operations assuring compliance with appropriate regulatory standards including but not limited to the Code of Federal Regulations (CFR), EMA Regulations, aseptic manufacturing, and/or Guidance documents such as U.S. FDA Points to Consider (PTC).

Responsibilities

  • Day-to-day activities of the manufacturing with respect to scheduling of production, operations and materials management activities.
  • Investigate and resolve problems.
  • Identify and implement process improvements.
  • Responsible for managing the training and development of personnel.
  • Responsible for interfacing and relationship development with all support departments (QC, QA, Facilities, Development, etc.) to assure production goals are met.
  • Tracking and trending critical process parameters and critical quality parameters.
  • Working with process development to review new process equipment compliance to GMP regulations and aseptic process requirements.

Qualifications

  • BS/BA degree required in biological sciences, biotechnology or life sciences.
  • Masters in biological sciences preferred.
  • 3 to 5 years of work experience in pilot or commercial biologics manufacturing plant under cGMP requirements.
  • 2 to 3 years prior management experience.

Research Associate - Gametocyte Production

The Research Associate will be involved in the malaria PfSPZ vaccine production process. This position involves aseptic techniques, maintenance of parasite cultures and other aspects of GMP Manufacturing including mosquito dissection; revision and development of SOPs and batch records for Gametocyte Production team; conducting standard membrane feeding assays (SMFA) and vailing PfSPZ vaccine. The incumbent is also expected to participate in research projects targeted at optimizing the efficiency and scaling up of procedures.

Qualified candidates must have a degree in Biology or related discipline and 3 years of relevant experience. A Master's degree is preferred. Excellent communication and interactive skills and the willingness to learn new experimental techniques are required. Experience with sterile technique, microscopy and cell culture is desirable. A background in bio-engineering is a plus. Permanent eligibility to work in the US is required.


Calibration/Metrology Technician - Summer Intern/Employment

The Calibration/Metrology Technician will organize calibration data into an online server-based database (Blue Mountain) used for FDA compliance. Duties to include scanning documents into Blue Mountain, cross-checking calibration certificates with NIST (National Institute of Science and Technology) Standards, and organizing the current local system for data management. Other duties may be assigned as time permits.

Candidates must be highly motivated with a keen eye for detail. The ideal candidate will have a strong background in computers and data entry with a focus in Metrology preferred. Preferred background: science, engineering, computer science.

 

disclaimer     site map

copyright(c) 2003-2017, Sanaria Inc., all rights reserved

Denver web designer